Retinal Vein Occlusion (RVO)

Retinal vein occlusion (RVO) is a common form of retinal vascular disease, especially in middle-aged and older individuals. It occurs when the vein providing outflow of blood from the retina becomes blocked and can cause vision loss, often suddenly. Unfortunately, reversing or opening of the blocked vein is not a possible treatment. While many patients will regain vision, it rarely returns to normal.

There are two types of RVO:

Branch (BRVO) occurs when the blockage is located in a branch of the retinal vein.
Central (CRVO) occurs when the blockage is located at the optic nerve.

Risk factors that can contribute to RVO include:

• Diabetes
• Atherosclerosis (hardening of the arteries)
• High blood pressure (hypertension)
• Other eye conditions, such as glaucoma, macular edema, or vitreous hemorrhage

Treatment for the complications of BRVO has historically involved laser therapy (which can lead to irreversible blind spots and loss of night vision). Patients with CRVO are often treated with frequent intravitreal injections. Today, Alimera Sciences is studying the safety and efficacy of ILUVIEN^®.  ILUVIEN is a tiny intravitreal insert being studied to deliver a daily, submicrogram dosage of the corticosteroid fluocinolone acetonide, to the retina for up to three years. Learn More about ILUVIEN >>